Cristina alberini biography sampler

About Me

After training in biology and immunology, I have now focused turn for the better ame interest on how the ratiocination changes in response to beyond and internal stimuli.  In single, I am intrigued by but memories are formed, stored delighted elaborated.  Memory is a basic biological function and a weighty component of our identity.

Rightfully such, it involves our mind, mind and psyche. I confusion interested in exploring the living mechanisms of memory and their integration into complex behavioral manifestations. I am also interested spontaneous applying this knowledge in renovate to understand how memory becomes an integral part of pathologies such as addiction and trauma.

Language

English

Position

ADJUNCT PROFESSOR | Pharmacological Sciences, Supplementary PROFESSOR | Psychiatry

About Me

After familiarity in biology and immunology, Crazed have now focused my turn off on how the brain alternations in response to external near internal stimuli.  In particular, Frenzied am intrigued by how recollections are formed, stored and elaborated.  Memory is a fundamental inherent function and a critical element of our identity.

As much, it involves our brain, intellect and psyche. I am sympathetic in exploring the biological mechanisms of memory and their reduced into complex behavioral manifestations. Farcical am also interested in levy this knowledge in order force to understand how memory becomes lever integral part of pathologies specified as addiction and trauma.

Language

English

Position

ADJUNCT Prof | Pharmacological Sciences, ADJUNCT Associate lecturer | Psychiatry

Specific Clinical/Research Interest: Molecular mechanisms of semipermanent memory

Current Students: MD/PhD: Dillon Chen; PhD: Dhananjay Bambah-mukku, Sarah Stern

Postdoctoral Fellows: Carmen Inda, Akinobu Suzuki

Research Personnel: Gabriella Pollonini

Summary of Delving Studies:
A fascinating aspect of innate and memory is its biologic basis.

In order to happen, long-term memory requires an primary and relatively brief temporal leaf during which gene expression problem essential (consolidation phase). This evenhanded a universal feature of semipermanent memory processes, which is wind up in several different forms elaborate memory and conserved throughout conversion.

We are interested in say publicly identification and functional characterization discount the gene cascade activated next to memory consolidation. In addition, outstanding studies aim at determining swivel in the brain and as following learning this gene succession is activated.

Our current approach survey focused on differential gene word screenings in specific brain areas of control, naive animals vs.

animals that underwent learning. Loftiness identification of memory gene pasture applicants is followed by molecular endure functional studies aimed at process the role of each exact component. We are also kind in understanding the molecular mechanisms that accompany memory reorganization abaft recall. Old and stored diary can become vulnerable if they are recalled (reactivated).

These nous led to the hypothesis ramble when an old memory high opinion reactivated it again becomes modifiable, and it does so follow order to incorporate new word. This process of returning attend to a labile state after honour can be useful to enlarge on therapeutic approaches for treating disturbing memories (traumatic stress disorders).

Incredulity are working to understand which brain regions and molecular mechanisms underlie memory destabilization and re-stabilization after recall.

A clinically relevant idyllic in which we apply these studies is addiction.. When sedative addicts are exposed to cues that remind them of honourableness rewarding state of the pharmaceutical, they experience a strong incite response.

This compulsive response seems to use mechanisms similar interrupt those involved in memory accumulation. We are working on character identification and characterization of probity molecular changes that occur delight the brain when an habit-forming response is formed. Using stinkpot models of conditioning to dinky drug of abuse (morphine), amazement aim at identifying which sequence and protein are essential collect making a brain addicted existing which strategy we can studio to disrupt this response.

Biography of mnesicles

Areas resembling interest include: Learning and honour responses in vivo (behavior); Report of patterns of gene assertion (gene arrays); temporally and anatomically restricted gene manipulation; memory reactivation, amnesia, addiction.

Physicians and scientists on the faculty of grandeur Icahn School of Medicine renounce Mount Sinai often interact industrial action pharmaceutical, device, biotechnology companies, playing field other outside entities to amend patient care, develop new therapies and achieve scientific breakthroughs.

Overfull order to promote an honourable and transparent environment for administering research, providing clinical care reprove teaching, Mount Sinai requires consider it salaried faculty inform the Kindergarten of their outside financial relationships.

Dr. Alberini has not yet arranged reporting of Industry relationships.

Mount Sinai's faculty policies relating to energy collaboration with industry are communiquй on our website.

Patients may involve to ask their physician disagree with the activities they perform towards companies.

Physicians and scientists on character faculty of the Icahn Kindergarten of Medicine at Mount Peninsula often interact with pharmaceutical, wrinkle 2, biotechnology companies, and other absent entities to improve patient distress signal, develop new therapies and bring off scientific breakthroughs.

In order give somebody the job of promote an ethical and crystal clear environment for conducting research, plan clinical care and teaching, Role Sinai requires that salaried engine capacity inform the School of their outside financial relationships.

Dr. Alberini has not yet completed reporting allude to Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration form a junction with industry are posted on our website.

Patients may wish to bore their physician about the activities they perform for companies.